Recombinant Rat GRO/KC (CXCL1)

Product Details

Catalog Number: 400-10

Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), KC (murine), CINC (rat)

AA Sequence: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P14095

Gene ID: 81503

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

Cross Reactivity Cited in References:

Mouse, Rat

Country Of Origin: USA

Not for human use.

Research Interest

Angiogenesis/Cardiovascular

Recent Citations

First Author

Cai, Y

Title

Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.

Citation

Pharmacology Research and Perspectives; 8(1) pge00559

PubMed ID

31956418

First Author

Boespflug, N D

Title

ATF3 is a novel regulator of mouse neutrophil migration.

Citation

Blood; 123(13) pg2084-93

PubMed ID

24470589

First Author

Abu-Taha, M

Title

Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.

Citation

Journal of immunology (Baltimore, Md. : 1950); 183(2) pg1393-402

PubMed ID

19553526

Chemokines