单克隆抗体

Biogems

Anti-Human CD152 (CTLA-4) Purified (Clone#: BNI3)

产品详情

产品编号: 14611-20
产品描述:
The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.

Source: Isotype: Mouse IgG2a, kappa; Clone#: BNI3

Note:

Product supplied by Biogems

Cross Reactivity:
Human
Research Interest

Country Of Origin: USA

Not for human use.