单克隆抗体

Biogems

Anti-Human/Mouse CD11b Purified (Clone#: M1/70)

产品详情

产品编号: 03221-20
产品描述:
The M1/70 monoclonal antibody specifically reacts with the 170 kDa αM integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.

Source: Isotype: Rat IgG2b, kappa; Clone#: M1/70

Note:

Product supplied by Biogems

Cross Reactivity:
Human, Mouse
Research Interest

Country Of Origin: USA

Not for human use.