单克隆抗体

Biogems

Anti-Human CD184 (CXCR4) Purified (Clone#: 12G5)

产品详情

产品编号: 16911-20
产品描述:
The 12G5 monoclonal antibody specifically bind to human CD184 (CXCR4), a seven-transmembrane G-protein-coupled receptor. It is widely expressed on endothelial cells, hematopietic cells, and also on naïve T cell subsets. CD184 is the receptor for SDF-1 and an alternative receptor for HIV-1. The 12G5 antibody is reported to inhibit SDF-1 induced chemotaxis and calcium influx and some CD4-dependent infections of HIV-1.

Source: Isotype: Mouse IgG2a, kappa; Clone#: 12G5

Note:

Product supplied by Biogems

Cross Reactivity:
Human
Research Interest

Country Of Origin: USA

Not for human use.