单克隆抗体

Biogems

Anti-Human CD28 Purified (Clone#: CD28.2)

产品详情

产品编号: 10311-20
产品描述:
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.

Source: Isotype: Mouse IgG1, kappa; Clone#: CD28.2

Note:

Product supplied by Biogems

Cross Reactivity:
Human
Research Interest

Country Of Origin: USA

Not for human use.