单克隆抗体

Biogems

Anti-Mouse CD279 (PD-1) SAFIRE Purified (Clone#: RMP1-14)

产品详情

产品编号: 31822-25
产品描述:
The RMP1-14 monoclonal antibody specifically reacts with mouse Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The RMP1-14 is reported to block the binding of B7-H1 and B7-DC ligands to the PD-1 receptor.

Source: Isotype: Rat IgG2a, kappa; Clone#: RMP1-14

Note:

Product supplied by Biogems

SAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications.

Cross Reactivity:
Mouse
Research Interest

Country Of Origin: USA

Not for human use.