单克隆抗体

Biogems

Anti-Human CD40 SAFIRE Purified (Clone#: 5C3)

产品详情

产品编号: 02511-25
产品描述:
The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Source: Isotype: Mouse IgG1, kappa; Clone#: 5C3

Note:

Product supplied by Biogems

SAFIRE (Sodium Azide Free Immensely Reduced Endotoxin) products are BioGems’ line of functional antibodies that can be used for activation, blocking, and neutralization studies. They are manufactured carrier and sodium azide free, with immensely reduced endotoxin levels of 0.01 EU/ug or lower for in vivo and in vitro applications.

Cross Reactivity:
Human
Research Interest

Country Of Origin: USA

Not for human use.