小分子

Biogems

NU 7441

产品详情

产品编号: 5039598
产品描述:

NU 7441 is a selective and potent DNA-PK inhibitor (IC50 14nM) and P13K inhibitor (IC50 5uM). It is reported enhance the cytotoxic effects of radiation in cancer cell lines and potentiate the effects of etoposide and doxorubicin. NU 7441 is also reported to enhance the efficiency of CRISPR-Cas9 mediated homology-directed repair (HDR) 2 to 4 fold and decrease nonhomologous end-joining (NHEJ) frequency by 2 fold.

Synonyms: KU57788, KU 57788, NU-7441, NU7441

Application:

Formulation:
Crystalline solid
Chemical Name:
8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one
Molecular Formula:

C25H19NO3S

Molecular Weight:
413.5
CAS Number:
503468-95-9
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.