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GMP级别细胞因子

PeproGMP® Recombinant Human Flt3-Ligand

产品详情

产品编号: GMP300-19
产品描述:

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells.  Multiple isoforms of Flt3-Ligand have been identified.  The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform.

Additional product information and specifications are provided on the Certificate of Analysis.

Note: All of PeproTech's GMP products are manufactured using animal-derived component free materials.

Source: E.coli

Synonyms: Fms-related tyrosine kinase 3 ligand, Flt3L

AA Sequence: MTQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Accession Number: P49771

Gene ID: 2322

Research Interest

Country Of Origin: USA

Not for human use.