Recombinant Human FGF-acidic 0 评论Submit a Review 产品详情 产品编号: 100-17A 产品描述: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta AA Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 16.8 kDa Accession Number: P05230 Gene ID: 2246 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Cow, Hagfish, Hamster, Human, Leech, Mouse, Pig, Rat, Shark, Squid References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 骨/骨骼系统/软骨 癌症 细胞培养 FGF超家族 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Haensel, D 标题 LY6D marks pre-existing resistant basosquamous tumor subpopulations. 文献引用 Nature Communications; 13(1) pg7520 PubMed Id 36473848 第一作者 Hu, H 标题 Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. 文献引用 Cancer Cell; 39(11) pg1531-1547.e10 PubMed Id 34624218 第一作者 Yu, K 标题 Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses. 文献引用 Cell Reports; 35(12) pg109273 PubMed Id 34161766