Animal-Free Recombinant Human FGF-acidic 0 评论Submit a Review 产品详情 产品编号： AF-100-17A 产品描述： FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta AA Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 16.8 kDa Accession Number: P05230 Gene ID: 2246 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Cow, Human, Mouse, Pig, Rat, Shark, Squid References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 骨/骨骼系统/软骨 癌症 细胞培养 FGF超家族 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Music, E 标题 Transforming growth factor-beta stimulates human bone marrow-derived mesenchymal stem/stromal cell chondrogenesis more so than kartogenin 文献引用 Scientific Reports; 10(1) pg8340 PubMed Id 32433527 第一作者 Boon, R 标题 Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines 文献引用 Nature Communications; 11(1) pg1393 PubMed Id 32170132 第一作者 Chua, V 标题 Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma 文献引用 EMBO Molecular Medicine; 11(2) PubMed Id 30610113
