Recombinant Human IFN-γ 1 评论Submit a Review 产品详情 产品编号: 300-02 产品描述: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues. Source: E.coli Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF AA Sequence: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 16.8 kDa Accession Number: P01579.1 Gene ID: 3458 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Fish + Virus, Human, Human + Bacteria, Human + Hamster, Human + Mouse, Human + Virus, Mandarin Fish, Monkey, Mouse, Pig, Rabbit, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 艾滋病/HIV 血管生成/心血管 癌症 糖尿病/体重调节 免疫系统 神经生物学 干细胞&分化 过敏 移植 product.subtitle.recentcitations 第一作者 Amri, N 标题 Blood Endothelial-Cell Extracellular Vesicles as Potential Biomarkers for the Selection of Plasma in COVID-19 Convalescent Plasma Therapy. 文献引用 Cells; 11(19) PubMed Id 36231083 第一作者 Duweb, A 标题 The SC cell line as an in vitro model of human monocytes. 文献引用 Journal of Leukocyte Biology; 112(4) pg659-668 PubMed Id 35355303 第一作者 George, S 标题 Protocol to drive human monocyte-to-macrophage polarization in vitro using tumor conditioned media. 文献引用 STAR Protocols; 3(4) pg101666 PubMed Id 36125932 product.subtitle.productreviews 现有评论 Confirmed dose response Used in an experiment and saw a nice dose response effect 来自: Lucia | 日期: 2021/8/24 × Confirmed dose response Used in an experiment and saw a nice dose response effect 来自: Lucia | 日期: 2021/8/24 Close