Animal-Free Recombinant Human IL-8 (CXCL8) (72 a.a.) 0 评论Submit a Review 产品详情 产品编号： AF-200-08M 产品描述： IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 AA Sequence: SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.4 kDa Accession Number: P10145 Gene ID: 3576 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 血管生成/心血管 细胞凋亡 化学趋化 免疫系统 炎症 神经生物学 创伤修复 过敏 移植 product.subtitle.recentcitations 第一作者 Whittall, C 标题 A chemokine self-presentation mechanism involving formation of endothelial surface microstructures. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 190(4) pg1725-36 PubMed Id 23325889 第一作者 Madenspacher, J H 标题 Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. 文献引用 The Journal of Biological Chemistry; 287(52) pg43730-40 PubMed Id 23118226 第一作者 Raghuwanshi, S K 标题 The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 189(6) pg2824-32 PubMed Id 22869904
