Recombinant Human LEC (CCL16) 0 评论Submit a Review 产品详情 产品编号： 300-44 产品描述： LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes, but not neutrophils. Recombinant Human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Liver-Expressed Chemokine, CCL16, NCC-4, HCC-4, LMC, LCC-1, MTN-1, IL-10-inducible chemokine AA Sequence: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract total human monocytes using a concentration range of 10-100 ng/ml. Calculated Molecular Weight: 11.2 kDa Accession Number: O15467 Gene ID: 6360 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 化学趋化 免疫系统 创伤修复 product.subtitle.recentcitations 第一作者 Lee, A W 标题 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 文献引用 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 第一作者 Alenazi, Y 标题 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 文献引用 Scientific Reports; 8(1) pg6333 PubMed Id 29679010 第一作者 Yagawa, Y 标题 Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. 文献引用 Scientific Reports; 7(1) pg15996 PubMed Id 29167448
