Recombinant Human Maspin 0 评论Submit a Review 产品详情 产品编号： 130-12 产品描述： Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells, but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the contribution of maspin to the inhibition of angiogenesis, and its ability to preferentially promote apoptosis of tumor cells. Recombinant Human Maspin is a 42.1 kDa non-glycosylated protein containing 375 amino acid residues. Source: E.coli Synonyms: SerpinB5, Protease inhibitor 5 AA Sequence: MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP Purity: ≥ 97% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 42.1 kDa Accession Number: P36952 Gene ID: 5268 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 细胞凋亡 癌症 免疫系统 创伤修复 product.subtitle.recentcitations 第一作者 Reina, J 标题 Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation. 文献引用 FEBS Open Bio; 9(7) pg1174-1183 PubMed Id 31144423
