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趋化因子

Recombinant Human MCP-3 (CCL7)

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产品详情

产品编号: 300-17
产品描述:
Recombinant Human MCP-3 (CCL7)

The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-3 is a 9.0 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-3, CCL7, MARC

AA Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml.

Recombinant Human MCP-3 (CCL7) Biological Activity Graph

Calculated Molecular Weight: 9 kDa

Accession Number: P80098

Gene ID: 6354

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Darlot, B
标题
Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction.
文献引用
The Journal of Biological Chemistry; 295(32) pg10926-10939
PubMed Id
第一作者
Lee, A W
标题
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
文献引用
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id
第一作者
Alenazi, Y
标题
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
文献引用
Scientific Reports; 8(1) pg6333
PubMed Id