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趋化因子

Recombinant Human MIP-3β (CCL19)

产品详情

产品编号: 300-29B
产品描述:
Recombinant Human MIP-3β (CCL19)

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Human MIP-3β is an 8.8 kDa protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.

Calculated Molecular Weight: 8.8 kDa

Accession Number: Q99731

Gene ID: 6363

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Du, Y
标题
Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.
文献引用
The Journal of Experimental Medicine; 219(7)
PubMed Id
第一作者
Gurusamy, M
标题
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
文献引用
Nature Communications; 12(1) pg6798
PubMed Id
第一作者
Lee, A W
标题
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
文献引用
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id

product.subtitle.productreviews

现有评论
CCL19
This product works very well at a concentration of 10 ng/ml.
来自:  Meshach | 日期:  2020/7/22