Animal-Free Recombinant Human RANTES (CCL5) 0 评论Submit a Review 产品详情 产品编号： AF-300-06 产品描述： RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Human RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta AA Sequence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P13501 Gene ID: 6352 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Human + Virus, References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 血管生成/心血管 化学趋化 免疫系统 炎症 神经生物学 创伤修复 过敏 移植 product.subtitle.recentcitations 第一作者 Whittall, C 标题 A chemokine self-presentation mechanism involving formation of endothelial surface microstructures. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 190(4) pg1725-36 PubMed Id 23325889 第一作者 Swaminathan, G 标题 A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages. 文献引用 PLoS Pathogens; 8(9) pge1002937 PubMed Id 23028330 第一作者 Yang, D 标题 High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses. 文献引用 The Journal of Experimental Medicine; 209(1) pg157-71 PubMed Id 22184635
