Recombinant Human/Murine FGF-8b 0 评论submitareview 产品详情 产品编号： 100-25 产品描述： FGF-8 (FGF-8b) is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF-8A and B are identical, unlike human and mouse FGF-8E and F, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant Human/Murine FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF-8 AA Sequence: MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 5 ng/ml, corresponding to a specific activity of ≥ 2 x 105 units/mg. Calculated Molecular Weight: 22.5 kDa Accession Number: P55075 Gene ID: 2253 Note: 1mg will be provided as 2x500μg crossreactivity: Chicken, Hamster, Human, Mouse, Rabbit, Rat Research Interest 血管生成/心血管 骨/骨骼系统/软骨 癌症 FGF超家族 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 References PubMed SDS Product Line Country Of Origin: USA Not for human use.
