Recombinant Murine GM-CSF 4 评论Submit a Review 产品详情 产品编号： 315-03 产品描述： GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues. Source: E.coli Synonyms: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α AA Sequence: MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 14.2 kDa Accession Number: P01587 Gene ID: 12981 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Leech, Mouse, Rat, Trout References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 癌症 细胞培养 免疫系统 炎症 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Li, Y 标题 Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis. 文献引用 Molecular Oncology; 16(15) pg2861-2880 PubMed Id 35665592 第一作者 Hooper, K M 标题 V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy. 文献引用 The Journal of Cell Biology; 221(6) PubMed Id 35511089 第一作者 Diethelm, P 标题 LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response. 文献引用 European Journal of Immunology; 52(6) pg924-935 PubMed Id 35344223 product.subtitle.productreviews 现有评论 Excellent product We have been using this product for 2 yrs for Bone marrow derived dendritic cell experiments and I never disappointed with the results. I highly recommend this product to our collaborators. 来自: Chetan | 日期: 2020/7/8 × Excellent product We have been using this product for 2 yrs for Bone marrow derived dendritic cell experiments and I never disappointed with the results. I highly recommend this product to our collaborators. 来自: Chetan | 日期: 2020/7/8 Close Great product This cytokine was used to stimulate various immune cells extracted from spleen and bone marrow of mice for the past few years with great performance. 来自: Jin | 日期: 2020/7/21 × Great product This cytokine was used to stimulate various immune cells extracted from spleen and bone marrow of mice for the past few years with great performance. 来自: Jin | 日期: 2020/7/21 Close mGMCSF Great for deriving DCs from BM. 来自: Kevin | 日期: 2020/8/26 × mGMCSF Great for deriving DCs from BM. 来自: Kevin | 日期: 2020/8/26 Close BMDCs we used this product for BMDCs in vitro maduration. 来自: Aitziber | 日期: 2020/8/26 × BMDCs we used this product for BMDCs in vitro maduration. 来自: Aitziber | 日期: 2020/8/26 Close
