Animal-Free Recombinant Murine IFN-γ 0 评论Submit a Review 产品详情 产品编号: AF-315-05 产品描述: IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes, as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting, cells and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant Murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF AA Sequence: MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg. Calculated Molecular Weight: 15.6 kDa Accession Number: P01580 Gene ID: 15978 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 艾滋病/HIV 血管生成/心血管 癌症 糖尿病/体重调节 免疫系统 神经生物学 干细胞&分化 过敏 移植 product.subtitle.recentcitations 第一作者 Hooper, K M 标题 V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy. 文献引用 The Journal of Cell Biology; 221(6) PubMed Id 35511089 第一作者 Tanyi, J L 标题 Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer 文献引用 NPJ Vaccines; 6(1) pg36 PubMed Id 33723260 第一作者 Li, S 标题 The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling. 文献引用 Cell Reports; 34(3) pg108631 PubMed Id 33472079