Recombinant Murine IL-3 2 评论Submit a Review 产品详情 产品编号： 213-13 产品描述： IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoiesis, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is a species-specific, variably glycosylated cytokine. Recombinant Murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues. Source: E.coli Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor AA Sequence: MDTHRLTRTL NCSSIVKEII GKLPEPELKT DDEGPSLRNK SFRRVNLSKF VESQGEVDPE DRYVIKSNLQ KLNCCLPTSA NDSALPGVFI RDLDDFRKKL RFYMVHLNDL ETVLTSRPPQ PASGSVSPNR GTVEC Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 15.1 kDa Accession Number: P01586 Gene ID: 16187 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Gerbil, Human, Monkey, Mouse, Mouse + Human, Mouse + Parasite, Mouse + Virus, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 癌症 细胞培养 糖尿病/体重调节 免疫系统 干细胞&分化 product.subtitle.recentcitations 第一作者 Dai, Y 标题 Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization. 文献引用 Cell Reports; 40(12) pg111361 PubMed Id 36130501 第一作者 Weissman, R 标题 MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis. 文献引用 Leukemia; 36(4) pg1139-1149 PubMed Id 34785791 第一作者 Ahmed, N 标题 Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. 文献引用 The Journal of Experimental Medicine; 219(1) PubMed Id 34817548 product.subtitle.productreviews 现有评论 Better than any other brand Used to treat cells but used different company products and they weren't got delivered it as fast as this one 来自: Cansu | 日期: 2020/7/28 × Better than any other brand Used to treat cells but used different company products and they weren't got delivered it as fast as this one 来自: Cansu | 日期: 2020/7/28 Close Recombinant Murine IL-3 We use this product to make stock dilutions, and store at -20. until we need to prep more murine media. They had always worked well post thaw 来自: Nichole | 日期: 2020/8/26 × Recombinant Murine IL-3 We use this product to make stock dilutions, and store at -20. until we need to prep more murine media. They had always worked well post thaw 来自: Nichole | 日期: 2020/8/26 Close
