Recombinant Murine IL-33 0 评论Submit a Review 产品详情 产品编号： 210-33 产品描述： IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, to activate NF-κB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant Murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues. Source: E.coli Synonyms: Interleukin-33, IL-1 F11, NF-HEV AA Sequence: SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 17.5 kDa Accession Number: Q8BVZ5 Gene ID: 77125 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 100μg is the largest vial size for this product. Larger sizes supplied as multiple 50μg and/or 100μg vials. crossreactivity: Human, Monkey, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 免疫系统 炎症 product.subtitle.recentcitations 第一作者 Liu, C 标题 Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells 文献引用 Cell Research; 31(10) pg1106-1122 PubMed Id 34239074 第一作者 Drube, S 标题 IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction. 文献引用 Immunology; 163(1) pg86-97 PubMed Id 33427298 第一作者 Leimkühler, N B 标题 Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. 文献引用 Cell Stem Cell; 28(4) pg637-652.e8 PubMed Id 33301706
