Recombinant Murine JE/MCP-1 (CCL2) 0 评论Submit a Review 产品详情 产品编号： 250-10 产品描述： The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Murine JE is a 13.8 kDa protein containing 125 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine) AA Sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml. Calculated Molecular Weight: 13.8 kDa Accession Number: P10148 Gene ID: 20296 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Monkey, Mouse, Rabbit, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 血管生成/心血管 癌症 化学趋化 免疫系统 炎症 神经生物学 创伤修复 过敏 product.subtitle.recentcitations 第一作者 Wang, W 标题 Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer 文献引用 Nature Communications; 12(1) pg4441 PubMed Id 34290255 第一作者 Zhang, Y 标题 MED1 Deficiency in Macrophages Accelerates Intimal Hyperplasia via ROS Generation and Inflammation. 文献引用 Oxidative Medicine And Cellular Longevity; 2021 pg3010577 PubMed Id 34853629 第一作者 Jeong, Y H 标题 Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenes. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 205(3) pg760-766 PubMed Id 32540996
