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趋化因子

Recombinant Murine LIX (CXCL6) (70 a.a.)

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产品详情

产品编号: 250-36
产品描述:
Recombinant Murine LIX (CXCL6) (70 a.a.)

CXCL6, also known as LIX in mice, is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX, LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that binds to the CXCR1 and CXCR2 receptors. Recombinant Murine LIX is a 7.6 kDa protein consisting of amino acid residues 9-78 of the full length LIX protein (70 amino acids).

Source: E.coli

AA Sequence: TELRCVCLTV TPKINPKLIA NLEVIPAGPQ CPTVEVIAKL KNQKEVCLDP EAPVIKKIIQ KILGSDKKKA

Synonyms: CXCL6, GCP-2 (human), Granulocyte Chemotactic Protein-2

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Recombinant Murine LIX (CXCL6) (70 a.a.) Biological Activity Graph

Calculated Molecular Weight: 7.6 kDa

Accession Number: P50228

Gene ID: 20311

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Singh, K
标题
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
文献引用
Scientific Reports; 7(1) pg4267
PubMed Id
第一作者
Rousselle, A
标题
CXCL5 limits macrophage foam cell formation in atherosclerosis.
文献引用
The Journal of Clinical Investigation; 123(3) pg1343-7
PubMed Id
第一作者
Mei, J
标题
CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection.
文献引用
Immunity; 33(1) pg106-17
PubMed Id