Recombinant Murine TPO 1 评论Submit a Review 产品详情 产品编号: 315-14 产品描述: TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets. Human and murine TPO exhibit cross-species reactivity. Recombinant Murine TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein. Source: E.coli Synonyms: Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF AA Sequence: SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg. Calculated Molecular Weight: 18.7 kDa Accession Number: P40226 Gene ID: 21832 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Mouse + Virus, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 细胞培养 免疫系统 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Ahmed, N 标题 Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. 文献引用 The Journal of Experimental Medicine; 219(1) PubMed Id 34817548 第一作者 Abbonante, V 标题 Ablation of collagen VI leads to the release of platelets with altered function. 文献引用 Blood Advances; 5(23) pg5150-5163 PubMed Id 34547769 第一作者 Gerosa, R C 标题 CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis. 文献引用 Blood Advances; 5(23) pg5002-5015 PubMed Id 34581809 product.subtitle.productreviews 现有评论 Recombinant Murine SCF We use this product in our mouse media, it works well! 来自: Nichole | 日期: 2020/8/26 × Recombinant Murine SCF We use this product in our mouse media, it works well! 来自: Nichole | 日期: 2020/8/26 Close