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生长因子和细胞因子

Recombinant Rat FGF-10

产品详情

产品编号: 400-42
产品描述:

FGF‐10 is a heparin‐binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF‐10 is most related to KGF/FGF‐7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Rat FGF‐10 is a 20.15 kDa protein consisting of 180 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2

AA Sequence: MQALGQDMVS PEATNSSSSS SSSSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Assay #1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8).

Assay #2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 1-5 ng/ml.

Calculated Molecular Weight: 20.15 kDa

Accession Number: P70492

Gene ID: 25443

Research Interest

Country Of Origin: USA

Not for human use.