Recombinant Rat Fractalkine (CX3CL1) 0 评论Submit a Review 产品详情 产品编号: 400-26 产品描述: Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Fractalkine is, at this time, the only CXC3C chemokine that contains three amino acid residues between the first and second cysteine residues of the chemokine domain. The Fractalkine gene encodes for a 397 amino acid precursor protein containing a 24 amino acid signal sequence, a chemokine domain, and a "mucin-like stalk" sequence, which is followed by the transmembrane domain containing approximately 20 amino acids, and a C-terminal cytoplasmic domain. The extracellular chemokine domain contains 76 amino acid residues, including the four conserved cysteine residues found in other chemokines. Recombinant Human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Recombinant Rat Fractalkine is an 8.7 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Neurotactin, CX3CL1, FKN AA Sequence: QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQDAMKHLDHQTA ALTRNG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml. Calculated Molecular Weight: 8.7 kDa Accession Number: O55145 Gene ID: 89808 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 血管生成/心血管 细胞凋亡 癌症 化学趋化 免疫系统 炎症 神经生物学 创伤修复 product.subtitle.recentcitations 第一作者 Treacy, O 标题 Adenoviral transduction of mesenchymal stem cells: in vitro responses and in vivo immune responses after cell transplantation. 文献引用 PLoS ONE; 7(8) pge42662 PubMed Id 22880073