Recombinant Rat Resistin 0 评论Submit a Review 产品详情 产品编号: 400-35 产品描述: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that resistin expression is severely suppressed in obesity, and that it may act as a feedback regulator of Adipogenesis. Recombinant Rat Resistin is a 20.0 kDa, disulfide-linked, homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond. Source: E.coli Synonyms: FIZZ3, Adipose tissue-specific secretory factor, ADSF AA Sequence (monomer): PSMSLCPMDE AISKKINQDF SSLLPAAMKN TVLHCWSVSS RGRLASCPEG TTVTSCSCGS GCGSWDVRED TMCHCQCGSI DWTAARCCTL RVGS Purity: ≥ 97% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 20 kDa Accession Number: Q8K4J7 Gene ID: 246250 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 血管生成/心血管 糖尿病/体重调节 免疫系统 炎症