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Biogems

Ruxolitinib

产品详情

产品编号: 9414958
产品描述:

Ruxolitinib is a potent Janus-associated Kinase (JAK1 IC50 2.7nM, JAK2 IC50 4.5nM) inhibitor. JAK1 and JAK2 transduce cytokine-mediated signals and are involved in interferon-gamma signaling. Ruxolitinib is reported to block IL-6 signaling and inhibits the proliferation of erythroid progenitors.

Synonyms: INCB018424, Jakavi, Jakafi, INCB-018424

Application:

Formulation:
Crystalline solid
Chemical Name:
(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
Molecular Formula:

C17H18N6

Molecular Weight:
306.4
CAS Number:
941678-49-5
Purity:
≥98%

Note:

Product supplied by Biogems

Research Interest

Country Of Origin: USA

Not for human use.