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Research Areas
COVID-19
COVID-19 (SARS-CoV-2) has become a global concern and a center of interest for the scientific community, which is researching the virus from many different perspectives. PeproTech's products are frequently cited in publications exploring COVID-19 research, from its infection mechanisms to its response to anti-COVID-19 drugs. Below we have compiled a collection of COVID-19 related articles, which give insight into some of the progress being made, and a listing of the relevant products cited within these articles.
View References for PeproTech’s products in COVID-19 Research:
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
Author: Monteil, V
We have previously provided the first genetic evidence that angiotensin converting enzyme 2 (ACE2) is the critical receptor for severe acute respiratory syndrome coronavirus (SARS-CoV), and ACE2 protects the lung from injury, providing a molecular explanation for the severe lung failure and death due to SARS-CoV infections.
Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells.
Author: Stanifer, M
Severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is an unprecedented worldwide health problem that requires concerted and global approaches to stop the coronavirus 2019 (COVID-19) pandemic.
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Author: Bouhaddou, M
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds of thousands of people worldwide, highlighting an urgent need to develop antiviral therapies.
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.
Author: Li, Q
The spike protein of SARS-CoV-2 has been undergoing mutations and is highly glycosylated. It is critically important to investigate the biological significance of these mutations.
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
Author: Xiang, Z
COVID-19 is a public health emergency that has rapidly spread to over 200 countries and regions, and no effective treatment has been established to date.
Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses.
Author: Zhou, R
The SARS-CoV-2 pandemic has resulted in millions of infections, yet the role of host immune responses in early COVID-19 pathogenesis remains unclear.
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Author: Sekine, T
SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune protection against COVID-19.
Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium.
Author: Jacob, F
Neurological complications are common in patients with COVID-19.
Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2.
Author: Youk, J
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a present pandemic, infects human lung alveolar type 2 (hAT2) cells.
