Recombinant Human LAG-1 (CCL4L1) 0 评论Submit a Review 产品详情 产品编号: 300-58 产品描述: LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV-suppressive factor. Recombinant Human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues. Source: E.coli Synonyms: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21 AA Sequence: APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract CCR5-transfected cells using a concentration of 0.1-10.0 ng/ml Calculated Molecular Weight: 7.7 kDa Accession Number: Q8NHW4 Gene ID: 388372 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 化学趋化 免疫系统 创伤修复 product.subtitle.recentcitations 第一作者 Lee, A W 标题 A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. 文献引用 The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 第一作者 Alenazi, Y 标题 Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. 文献引用 Scientific Reports; 8(1) pg6333 PubMed Id 29679010