Animal-Free Recombinant Rat GM-CSF 0 评论Submit a Review 产品详情 产品编号： AF-400-23 产品描述： GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α AA Sequence: MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse FDC-P1 cells. The expected ED50 is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg. Calculated Molecular Weight: 14.5 kDa Accession Number: P48750 Gene ID: 116630 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 癌症 细胞培养 免疫系统 炎症 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Togni, M 标题 The adapter protein ADAP is required for selected dendritic cell functions. 文献引用 Cell communication and signaling : CCS; 10(1) pg14 PubMed Id 22672517 第一作者 Li, X 标题 Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection. 文献引用 PLoS ONE; 7(8) pge43512 PubMed Id 22927979 第一作者 Choudhury, M E 标题 A cytokine mixture of GM-CSF and IL-3 that induces a neuroprotective phenotype of microglia leading to amelioration of (6-OHDA)-induced Parkinsonism of rats. 文献引用 Brain and Behavior; 1(1) pg26-43 PubMed Id 22398979
