Recombinant Rat IL-15 0 评论Submit a Review 产品详情 产品编号: 400-24 产品描述: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant Rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues. Source: E.coli Synonyms: IL-T AA Sequence: MNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. Calculated Molecular Weight: 13.5 kDa Accession Number: P97604 Gene ID: 25670 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse, Rat References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell 艾滋病/HIV 细胞凋亡 癌症 细胞培养 免疫系统 神经生物学 干细胞&分化 product.subtitle.recentcitations 第一作者 Inngjerdingen, M 标题 A novel NKR-P1B(bright) NK cell subset expresses an activated CD25(+)CX(3)CR1(+)CD62L(-)CD11b(-)CD27(-) phenotype and is prevalent in blood, liver, and gut-associated lymphoid organs of rats. 文献引用 Journal of immunology (Baltimore, Md. : 1950); 188(6) pg2499-508 PubMed Id 22308308