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无动物成分细胞因子

Animal-Free Recombinant Human NT-3

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产品详情

产品编号: AF-450-03
产品描述:
Animal-Free Recombinant Human NT-3

NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous system, and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant Human NT-3 is a noncovalently linked homodimer of two 13.6 kDa polypeptide monomers (240 total amino acid residues).

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Neurotrophin-3, Neurotrophic factor, Nerve growth factor-2, NGF-2, HGNF

AA Sequence (monomer): MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to bind recombinant human TrkB Fc Chimera in a functional ELISA.

Calculated Molecular Weight: 27.2 kDa

Accession Number: P20783

Gene ID: 4908

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Feng, L
标题
Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.
文献引用
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 7(23) pg2002155
PubMed Id
第一作者
Floriddia, E M
标题
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
文献引用
Nature Communications; 11(1) pg5860
PubMed Id
第一作者
Zhang, W
标题
Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation.
文献引用
Stem Cell Reports; 15(1) pg185-197
PubMed Id