Recombinant Human INSL5/INSL7 Hybrid 0 ReviewsSubmit a Review Product Details Catalog Number: 130-05 Description: The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an insulin-like heterodimeric structure of two polypeptide chains held together by two inter-chain disulfide bonds. The INSL5/INSL7 hybrid contains the β-chain of INSL7 (Relaxin-3), linked to the α-chain of INSL5. The INSL5/INSL7 hybrid protein can specifically activate the G protein-coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant Human INSL5/INSL7 hybrid is a heterodimeric, 5.2 kDa protein consisting of a 27 amino acid β-chain linked to a 21 amino acid α-chain by two disulfide bonds. Source: E.coli Synonyms: None AA Sequence: A-Chain: QDLQTLCCTD GCSMTDLSAL CB-Chain: RAAPYGVRLC GREFIRAVIF TCGGSRW Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 5.2 kDa Accession Number: INSL5: Q9Y5Q6 INSL7: Q8WXF3 Gene ID: INSL5: 10022 INSL7: 117579 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Diabetes/Weight Regulation Lipid Metabolism Neurobiology