Organoid models include three-dimensional (3D) cell culture systems that closely resemble in vivo organs or tissue. These 3D systems reproduce the complex spatial morphology of differentiated tissue to allow biologically relevant cell-to-cell and cell-to-matrix interactions, which ideally will share similar physiological responses with in vivo differentiated tissues.
The major focus of future organoid studies, besides the study of developmental processes, will likely be in drug testing and disease modeling, including genetic, developmental and degenerative disorders, and cancer.
Organoids are another step towards in vitro construction of tissues and organs for transplantation into patients.
NOTE: PeproTech products support organoid research; however, PeproTech itself does not conduct research relating to organoids. This information is based on a collection of references and cumulative information provided by professional researchers.
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