Recombinant Human Eotaxin-2 (CCL24) 0 리뷰submitareview 제품 상세 카다로그 번호 300-33 제품 설명 Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3, including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 amino acid residues for the murine homolog, without C-terminal truncation). Eotaxin-2 contains the four conserved cysteine residues present in CC chemokines. Recombinant Human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues. Source: E.coli Synonyms: CCL24, MPIF-2, CkB-6 AA Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml. Calculated Molecular Weight: 8.8 kDa Accession Number: O00175 Gene ID: 6369 crossreactivity: Bacteria, Human, Mouse Research Interest Chemotaxis Immune System Wound Healing References PubMed SDS Product Line Country Of Origin: USA Not for human use.
