Recombinant Human Eotaxin-2 (CCL24)

제품 상세

카다로그 번호 300-33

제품 설명

Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3, including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 amino acid residues for the murine homolog, without C-terminal truncation). Eotaxin-2 contains the four conserved cysteine residues present in CC chemokines. Recombinant Human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

Source: E.coli

Synonyms: CCL24, MPIF-2, CkB-6

AA Sequence: VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.

Cross Reactivity:

Bacteria, Human , Mouse

Research Interest

Country Of Origin: USA

Not for human use.

Products Cited

Cross-Reactivity

Applications

300-33, 300-06, 300-08, 300-24,

Mouse

in vitro

Products Cited

Cross-Reactivity

Applications

300-21, 300-33,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-21, 300-33, 200-08M, 300-08, 300-24,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-06, 300-08, 300-29, 300-29A, 300-33,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-17, 300-24, 300-33, 300-36, 900-K31, 900-K33, 900-K69, 500-P37G, 500-P04G, 500-P04BT, 500-P04GBT, 500-P107BT, 500-P103G, 500-P103GBT, 500-P103GBT, 900-K35, 900-K167, 500-P37GBT, 500-P04, 500-P107,

Human

ELISA

900-K59, 900-K75, 900-K72,

Rat

ELISA

500-P76, 500-P78,

Rat

Immunostaining

Products Cited

Cross-Reactivity

Applications

100-11, 100-20, 300-11, 300-21, 300-31, 300-33, 300-36, AF-100-15, 100-00AB, 100-18B, 100-39, 300-04, 300-06, 300-08, 300-28A,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-21, 300-33, 300-48,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

100-14B, 300-21, 300-31, 300-33, 300-48, 300-55, 300-57, 300-06, 300-54,

Human

Western Blot

Products Cited

Cross-Reactivity

Applications

250-06, 300-11, 300-12, 300-14, 300-16, 300-20, 300-21, 300-26, 300-29A, 300-29B, 300-30, 300-31, 300-33, 300-34, 300-36, 300-38, 300-39, 300-40, 300-41, 300-43, 300-44, 300-46, 300-48, 300-55, 300-57, 200-08M, 250-04, 250-12, 250-37, 300-04, 300-06, 300-08, 300-09, 300-15, 300-17, 300-22, 300-24, 300-28A, 300-29, 300-35, 300-37, 300-45, 300-47, 300-50, 300-54, 300-56,

Bacteria

in vitro

Products Cited

Cross-Reactivity

Applications

250-01, 250-04, 250-06, 250-07, 250-10, 250-11, 250-12, 250-13, 250-15, 250-16, 250-17, 250-18, 250-20A, 250-20B, 250-22, 250-23, 250-24, 250-26, 250-27, 250-27B, 250-28, 250-29, 250-30, 250-32, 250-36, 250-37, 250-39,

Mouse

Binding Assay

300-34, 300-11, 300-15, 300-29B, 300-46, 300-48, 300-54, 300-08, 300-28A, 300-43, 300-45, 300-31, 300-36A, 300-14, 300-39, 300-55, 300-16, 300-28B, 300-22, 300-44, 300-33, 300-26, 300-38, 300-57, 300-24, 300-40, 300-41, 300-30, 300-12, 300-50, 300-47, 300-29A, 300-35, 300-17, 300-09, 300-56, 300-04, 300-21,

Human

in vitro

Products Cited

Cross-Reactivity

Applications

300-37, 300-04, 300-08, 300-56, 300-09, 300-58, 300-06, 300-17, 300-15, 300-21, 300-24, 300-38, 300-43, 300-44, 300-30, 300-34, 300-29B, 300-29A, 300-35, 300-36A, 300-29, 300-33, 300-48, 300-54, 300-11, 300-39, 300-40, 300-16, 300-22, 300-22B, 300-41, 300-14, 200-08, 300-26, 300-12, 300-46, 300-28A, 300-28B, 300-47, 300-50, 300-55, 300-31,

Human

Chemotaxis Assay

Chemokines