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Recombinant Human Apo-SAA1

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产品详情

产品编号: 300-53
产品描述:
Recombinant Human Apo-SAA1

Serum amyloid A proteins (SAA) represents a family of apolipoproteins that circulates in association with high-density lipoproteins (HDL). The level of Apo-SAA, normally 1-5 μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apolipoprotein. The human SAA gene codes for a 122 amino acid nonglycosylated polypeptide, which contains an 18 amino acid N-terminal sequence. Recombinant Human Apo-SAA1 is an 11.7 kDa protein containing 105 amino acid residues.

Source: E.coli

Synonyms: Serum amyloid A-1 protein

AA Sequence: MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 11.7 kDa

Accession Number: P0DJI8

Gene ID: 6288

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
White, M R
标题
Effects of serum amyloid protein A on influenza A virus replication and viral interactions with neutrophils.
文献引用
Journal of Leukocyte Biology; 110(1) pg155-166
PubMed Id
第一作者
Klooster, J P
标题
Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine
文献引用
Communications Biology; 4(1) pg631
PubMed Id
第一作者
Getachew, A
标题
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury.
文献引用
Iscience; 24(5) pg102483
PubMed Id