Recombinant Human FGF-10 7 ReviewsSubmit a Review Product Details Catalogue Number: 100-26 Description: FGF-10 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2 AA Sequence: MLGQDMVSPE ATNSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Assay #1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). The expected ED50 is 5 ng/ml corresponding to a specific activity of ≥ 2 x 10^6 units/mg. Assay #2:Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.5-15.0 ng/ml. Calculated Molecular Weight: 19.3 kDa Accession Number: O15520 Gene ID: 2255 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Chicken, Dog, Human, Mouse, Rat, Snake References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Fujimura, T Title Identifying a Lung Stem Cell Subpopulation by Combining Single-Cell Morphometrics, Organoid Culture, and Transcriptomics. Citation Stem cells (Dayton, Ohio); PubMed Id 37468433 First Author Tanaka, J Title Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication. Citation Nature Cell Biology; 24(11) pg1595-1605 PubMed Id 36253535 First Author Nguyen, V V Title A human kidney and liver organoid-based multi-organ-on-a-chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell-derived extracellular vesicles. Citation Journal Of Extracellular Vesicles; 11(11) pge12280 PubMed Id 36382606 product.subtitle.productreviews Existing reviews High quality product Critical components of organoid media are a set of growth factors and I've used products from peprotech for 6 years to culture colon and lung organoid. I'm really satisfied with all the growth factors from peprotech and my consistent results. From: Eun Joo | Date: 2020/7/8 × High quality product Critical components of organoid media are a set of growth factors and I've used products from peprotech for 6 years to culture colon and lung organoid. I'm really satisfied with all the growth factors from peprotech and my consistent results. From: Eun Joo | Date: 2020/7/8 Close organoids All batches/lots that we have used so far worked as expected for developing pancreatic oragnoids. From: Mitesh | Date: 2020/7/9 × organoids All batches/lots that we have used so far worked as expected for developing pancreatic oragnoids. From: Mitesh | Date: 2020/7/9 Close Excellent quality We utilize FGF10 as part of a specialized lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service from Peprotech. From: Dora | Date: 2020/7/24 × Excellent quality We utilize FGF10 as part of a specialized lung cancer organoid media for cancers which do not have EGFR mutations. We have had great results and excellent service from Peprotech. From: Dora | Date: 2020/7/24 Close FGF-10 for Organoid Culture We using human FGF-10 for Pancreas, Head and Neck, Lung Organoid culture media. Works for both human and mouse medias.Used on more than 200 organoid linesConsistent activity and next day delivery.Very cost effective than other suppliers. From: Hardik | Date: 2020/8/14 × FGF-10 for Organoid Culture We using human FGF-10 for Pancreas, Head and Neck, Lung Organoid culture media. Works for both human and mouse medias.Used on more than 200 organoid linesConsistent activity and next day delivery.Very cost effective than other suppliers. From: Hardik | Date: 2020/8/14 Close hFGF-10 for pancreatic organoids culture We have used this product as part of our organoid cell culture media and it works perfectly. From: Pilar | Date: 2020/8/27 × hFGF-10 for pancreatic organoids culture We have used this product as part of our organoid cell culture media and it works perfectly. From: Pilar | Date: 2020/8/27 Close Organoid culture Great for organoid culture (endometrial cells). Fast turn around on getting the product. From: Juan | Date: 2020/8/28 × Organoid culture Great for organoid culture (endometrial cells). Fast turn around on getting the product. From: Juan | Date: 2020/8/28 Close Great for organoids! We use this in most of our patient tumor organoid media and have wonderful results. From: Julie-Ann | Date: 2021/8/3 × Great for organoids! We use this in most of our patient tumor organoid media and have wonderful results. From: Julie-Ann | Date: 2021/8/3 Close
