Recombinant Human MIG (CXCL9) 0 评论Submit a Review 产品详情 产品编号: 300-26 产品描述: MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Human MIG is an 11.7 kDa protein containing 103 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Monokine Induced by Interferon-gamma, CXCL9 AA Sequence: TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 11.7 kDa Accession Number: Q07325 Gene ID: 4283 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse, References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 血管生成/心血管 化学趋化 免疫系统 炎症 创伤修复 移植 product.subtitle.recentcitations 第一作者 Du, Y 标题 Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. 文献引用 The Journal of Experimental Medicine; 219(7) PubMed Id 35640018 第一作者 Poosti, F 标题 Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide. 文献引用 Clinical & translational immunology; 11(2) pge1370 PubMed Id 35140938 第一作者 Gurusamy, M 标题 G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. 文献引用 Nature Communications; 12(1) pg6798 PubMed Id 34815397