Recombinant Human MIG (CXCL9) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-26 Description: MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Human MIG is an 11.7 kDa protein containing 103 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Monokine Induced by Interferon-gamma, CXCL9 AA Sequence: TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 11.7 kDa Accession Number: Q07325 Gene ID: 4283 crossreactivity: Bacteria, Human, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing Transplantation product.subtitle.recentcitations First Author Fagète, S Title Dual specificity of anti-CXCL10-CXCL9 antibodies is governed by structural mimicry. Citation The Journal of Biological Chemistry; 287(2) pg1458-67 PubMed Id 22041899 First Author Schweickart, V L Title CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines. Citation The Journal of Biological Chemistry; 275(13) pg9550-6 PubMed Id 10734104 First Author Bonacchi, A Title Signal transduction by the chemokine receptor CXCR3: activation of Ras/ERK, Src, and phosphatidylinositol 3-kinase/Akt controls cell migration and proliferation in human vascular pericytes. Citation The Journal of Biological Chemistry; 276(13) pg9945-54 PubMed Id 11136732
