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Recombinant Murine RANTES (CCL5)

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Product Details

Catalogue Number: 250-07
Description:

RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant Murine RANTES is a 7.8 kDa protein containing 68 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Regulation upon Activation Normal T cell Express Sequence, CCL5, SIS-delta

AA Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10-30 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P30882

Gene ID: 20304

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
He, H
Title
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
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Blood; 136(2) pg183-198
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First Author
Wang, Q
Title
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α.
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Nature Communications; 9(1) pg559
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First Author
Wright, D E
Title
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
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The Journal of Experimental Medicine; 195(9) pg1145-54
PubMed Id