Animal-Free Recombinant Human IL-15 0 리뷰Submit a Review 제품 상세 카다로그 번호 AF-200-15 제품 설명 IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Interleukin-15, IL-T AA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 12.9 kDa Accession Number: P40933 Gene ID: 3600 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Human + Hamster, Monkey, Mouse References PubMed SDS CoA 검색 Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell AIDS/HIV Apoptosis Cancer Cell Culture Immune System Neurobiology Stem Cells & Differentiation product.subtitle.recentcitations 제 1 저자 Eichholz, K 주제 A CAR RNA FISH assay to study functional and spatial heterogeneity of chimeric antigen receptor T cells in tissue 인용 Scientific Reports; 11(1) pg12921 PubMed ID 34155235 제 1 저자 Kluesner, M G 주제 CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells 인용 Nature Communications; 12(1) pg2437 PubMed ID 33893286 제 1 저자 Weng, R R 주제 Epigenetic modulation of immune synaptic-cytoskeletal networks potentiates γδ T cell-mediated cytotoxicity in lung cancer 인용 Nature Communications; 12(1) pg2163 PubMed ID 33846331