Recombinant Human CXCL16 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-55 Description: CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues, including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal "mucin-like stalk" sequence. The extracellular domain contains 89 amino acid residues (86 amino acid residues for the murine homolog). Recombinant Human CXCL16 is a 10.1 kDa protein containing 89 amino acid residues. Source: E.coli Synonyms: SRPSOX AA Sequence: NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml. Calculated Molecular Weight: 10.1 kDa Accession Number: Q9H2A7 Gene ID: 58191 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations First Author Du, Y Title Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation. Citation The Journal of Experimental Medicine; 219(7) PubMed Id 35640018 First Author Bouhaddou, M Title The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Citation Cell; 182(3) pg685-712.e19 PubMed Id 32645325 First Author Blanco-Melo, D Title Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. Citation Cell; 181(5) pg1036-1045.e9 PubMed Id 32416070