Recombinant Human GRO-α/MGSA (CXCL1) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-11 Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO-α/MGSA is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2. Source: E.coli Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity, MGSAα, NAP-3, GRO1 AA Sequence: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P09341 Gene ID: 2919 crossreactivity: Bacteria, Hamster, Human, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing product.subtitle.recentcitations First Author Rosenkilde, M M Title Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74. Citation The Journal of Biological Chemistry; 274(2) pg956-61 PubMed Id 9873037 First Author Tripathi, P Title Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1. Citation Stem Cell Reports; 9(2) pg667-680 PubMed Id 28712846 First Author Tiffany, H L Title Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. Citation The Journal of Experimental Medicine; 186(1) pg165-70 PubMed Id 9207005
