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Recombinant Murine FGF-acidic

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Product Details

Catalogue Number: 450-33A
Description:
Recombinant Murine FGF-acidic

FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta

AA Sequence: MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 5 x 106 units/mg.

Calculated Molecular Weight: 15.9 kDa

Accession Number: P61148

Gene ID: 14164

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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