Recombinant Murine RELMα 0 ReviewsSubmit a Review Product Details Catalogue Number: 450-26 Description: RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, are 85-94 amino acid, secreted proteins sharing a conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMα and resistin are secreted exclusively by adipocytes, while RELMβ is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMα are still unknown. Recombinant Murine RELMα is a 10.0 kDa monomeric protein containing 89 amino acid residues. Source: E.coli Synonyms: Resistin-like α, Cysteine-rich secreted protein FIZZ1 AA Sequence: MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Not available. Calculated Molecular Weight: 10 kDa Accession Number: Q9EP95 Gene ID: 57262 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Chicken, Mouse, Parasite, Pig Intestinal Worm, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Diabetes/Weight Regulation Immune System Inflammation product.subtitle.recentcitations First Author Kim, Y S Title The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells Citation Cell Death & Disease; 12(4) pg307 PubMed Id 33753732 First Author Su, C Title Hypoxia induced mitogenic factor (HIMF) triggers angiogenesis by increasing interleukin-18 production in myoblasts. Citation Scientific Reports; 7(1) pg7393 PubMed Id 28785068 First Author Jackson-Jones, L H Title IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha Citation European Journal of Immunology; 46(10) pg2311-2321 PubMed Id 27592711
