Growth Factors & Cytokines

Recombinant Murine RELMα

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Product Details

Catalogue Number: 450-26
Description:

RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, are 85-94 amino acid, secreted proteins sharing a conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELMα and resistin are secreted exclusively by adipocytes, while RELMβ is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELMα are still unknown. Recombinant Murine RELMα is a 10.0 kDa monomeric protein containing 89 amino acid residues.

Source: E.coli

Synonyms: Resistin-like α, Cysteine-rich secreted protein FIZZ1

AA Sequence: MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Not available.

Calculated Molecular Weight: 10 kDa

Accession Number: Q9EP95

Gene ID: 57262

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Su, C
Title
Hypoxia induced mitogenic factor (HIMF) triggers angiogenesis by increasing interleukin-18 production in myoblasts.
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Scientific Reports; 7(1) pg7393
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Kim, Y S
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The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells
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Cell Death & Disease; 12(4) pg307
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Herbert, D R
Title
Intestinal epithelial cell secretion of RELM-beta protects against gastrointestinal worm infection.
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The Journal of Experimental Medicine; 206(13) pg2947-57
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