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Animal-Free Cytokines

Animal-Free Recombinant Human MCP-1 (CCL2)

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제품 상세

카다로그 번호 AF-300-04
제품 설명
Animal-Free Recombinant Human MCP-1 (CCL2)

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Manufactured using all Animal-Free reagents.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)

AA Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.6 kDa

Accession Number: P13500

Gene ID: 6347

Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

제 1 저자
Cross, S A
주제
Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
인용
Journal of immunology (Baltimore, Md. : 1950); 187(10) pg5015-25
PubMed ID
제 1 저자
Ekert, J E
주제
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes.
인용
Fibrogenesis & tissue repair; 4(1) pg23
PubMed ID
제 1 저자
Vasina, E M
주제
Microparticles from apoptotic platelets promote resident macrophage differentiation.
인용
Cell death & disease; 2 pge211
PubMed ID