Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, prolactin plays an immunoegulatory role by stimulating the activities of ornithine decarboxylase and protein kinase C, which are important for the proliferation, differentiation, and function of lymphocytes. Recombinant Rat Prolactin is a 22.6 kDa globular protein containing 198 amino acid residues.
Mammotropin, Luterotropic hormone, Lutetropin
MLPVCSGGDC QTPLPELFDR VVMLSHYIHT LYTDMFIEFD KQYVQDREFI AKAINDCPTS SLATPEDKEQ AQKVPPEVLL NLILSLVHSW NDPLFQLITG LGGIHEAPDA IISRAKEIEE QNKRLLEGIE KIISQAYPEA KGNEIYLVWS QLPSLQGVDE ESKDLAFYNN IRCLRRDSHK VDNYLKFLRC QIVHKNNC
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.